Hualan Biological Engineering Inc.

Chinese maker of plasma-derived blood products, vaccines, and biosimilars

What Hualan Biological Engineering does

Hualan Biological collects human plasma and processes it into life-saving medicines such as albumin, clotting factors for hemophilia, and immunoglobulins used against rabies, tetanus, and hepatitis B. It also manufactures vaccines, most notably seasonal and quadrivalent flu shots, plus meningococcal, hepatitis B, rabies, and tetanus vaccines. A newer arm is developing lower-cost copies of blockbuster antibody drugs like rituximab, trastuzumab, adalimumab, and denosumab, most now in late-stage trials.

How Hualan Biological Engineering makes money

Revenue comes from selling blood products and vaccines to Chinese hospitals, CDCs, and distributors, with plasma sourced through its own licensed collection stations. Future growth is intended to come from commercializing its monoclonal antibody biosimilar pipeline.

Products & services

• Human serum albumin
• Human coagulation factor VIII and prothrombin complex concentrate
• Immunoglobulins (intravenous, rabies, hepatitis B, tetanus)
• Quadrivalent influenza virus split vaccine
• Meningococcal polysaccharide vaccines (A/C and ACYW135)
• Biosimilar pipeline: rituximab, trastuzumab, adalimumab, denosumab